Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625376 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CTSKCTSBCTSSCTSL | |
| SCHEMBL4634083 | 0.95 | ALDH1A1 (0.50) | ALDH1A1CTSKCTSBCTSSCTSL | |
| SCHEMBL4634087 | 0.95 | ALDH1A1 (0.50) | ALDH1A1CTSKCTSBCTSSCTSL | |
| SCHEMBL6654265 | 0.95 | ALDH1A1 (0.50) | ALDH1A1CTSKCTSBCTSSCTSL | |
| SCHEMBL8385337 | 0.94 | ALDH1A1 (0.49) | ALDH1A1CTSKCTSBCTSSCTSL | |
| SCHEMBL8187290 | 0.90 | CTSK (0.48) | ALDH1A1CTSKCTSBCTSSCTSL | |
| SCHEMBL6622988 | 0.86 | POLB (0.46) | ALDH1A1CTSKCTSBCTSSCTSL | |
| SCHEMBL7331165 | 0.86 | POLB (0.46) | ALDH1A1CTSKCTSBCTSSCTSL | |
| SCHEMBL9327734 | 0.86 | ALDH1A1 (0.50) | ALDH1A1CTSKCTSBCTSSCTSL | |
| SCHEMBL9807067 | 0.86 | ALDH1A1 (0.50) | ALDH1A1CTSKCTSBCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960108-B1 | MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2004-10-27 | — | — | EP | disclosed |
| US-6194451-B1 | PREVENT RELEASE TUMOR NECROSIS FACTOR; ANTIINFLAMMATORY AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2001-02-27 | — | — | US | disclosed |