Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 12/20 | 0.41 |
| ▸ | CTSS | P25774 | 9/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623922 | 0.85 | CTSK (0.44) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL18681498 | 0.85 | CA1 (0.43) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL19373028 | 0.85 | CTSK (0.44) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL20750960 | 0.85 | CA1 (0.43) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL23736310 | 0.80 | CA1 (0.40) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL1743765 | 0.80 | DGAT1 (0.34) | CA1CA2CA7CTSKKMT2A | |
| SCHEMBL29610548 | 0.78 | CA1 (0.49) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL1106536 | 0.78 | CA1 (0.49) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL4217171 | 0.78 | CA1 (0.49) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL20029331 | 0.78 | CTSK (0.46) | CA1CA2CA7CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | claimed |