Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624543 | 0.89 | ADORA2A (0.64) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6624830 | 0.87 | ADORA2A (0.68) | ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL6627840 | 0.85 | ADORA2A (0.56) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6622390 | 0.83 | ADORA2A (0.54) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6625938 | 0.82 | ADORA2A (0.58) | ADORA2AADORA1 | |
| SCHEMBL6625559 | 0.80 | ADORA2A (0.71) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6624814 | 0.77 | ADORA2A (0.54) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6624389 | 0.77 | ADORA2A (0.64) | ADORA2AADORA1 | |
| SCHEMBL2853416 | 0.76 | ADORA2A (0.73) | ADORA2AADORA1 | |
| SCHEMBL6629612 | 0.75 | ADORA3 (0.60) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976753-B1 | [1,2,4]TRIAZOLO[1,5-c]PYRIMIDINE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2004-01-02 | — | — | EP | disclosed |
| EP-0976753-A1 | [1,2,4]TRIAZOLO[1,5-c]PYRIMIDINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-02-02 | — | — | EP | disclosed |