Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RB1 | P06400 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6622618 | 0.84 | CDC42 (0.46) | PARP1HTR2ADRD2HTR2CKCNH2 | |
| SCHEMBL6624826 | 0.84 | PARP1 (0.45) | PARP1HTR2ADRD2HTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL6628628 | 0.83 | PARP1 (0.41) | PARP1HTR2ADRD2HTR2CKCNH2 | |
| SCHEMBL6623902 | 0.83 | PARP1 (0.44) | PARP1HTR2ADRD2HTR2CKCNH2 | |
| SCHEMBL6625432 | 0.82 | PARP1 (0.44) | PARP1HTR2ADRD2HTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL6624623 | 0.81 | PARP1 (0.41) | PARP1MAOBMAOAALDH1A1 | |
| SCHEMBL6623672 | 0.80 | PARP1 (0.41) | PARP1MAOBMAOAVCP | |
| SCHEMBL6627765 | 0.79 | PARP1 (0.44) | PARP1KDM4E | |
| SCHEMBL6625366 | 0.78 | HTT (0.48) | RB1PARP1MEN1RAB9AKMT2A | |
| SCHEMBL6624637 | 0.77 | POLB (0.40) | PARP1MAOBMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |