Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625012 | 0.87 | CNR1 (0.46) | CNR1HTR1ADRD2HTR7ALDH1A1 | |
| SCHEMBL6625246 | 0.83 | HTT (0.49) | CNR1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL7481341 | 0.82 | CNR1 (0.55) | CNR1ALDH1A1MAPTGRK5TYRO3 | |
| SCHEMBL6627885 | 0.80 | POLB (0.47) | CNR1HTR1ADRD2HTR7ALDH1A1 | |
| SCHEMBL6625273 | 0.80 | POLB (0.47) | CNR1HTR1ADRD2HTR7ALDH1A1 | |
| SCHEMBL6628115 | 0.77 | CNR1 (0.49) | CNR1HTR1ADRD2HTR7ALDH1A1 | |
| SCHEMBL6624722 | 0.77 | HTR1A (0.47) | HTR1ADRD2HTR7ALDH1A1MAPT | |
| SCHEMBL6623977 | 0.77 | MGAT2 (0.40) | CNR1HTR1ADRD2HTR7ALDH1A1 | |
| SCHEMBL6624454 | 0.77 | HTT (0.42) | HTR1ADRD2HTR7ALDH1A1MAPT | |
| SCHEMBL6167711 | 0.77 | CNR1 (0.50) | CNR1ALDH1A1GRK5TYRO3DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373219-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002081453-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER SA (FR) | 2002-10-17 | — | — | WO | disclosed |