Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625012 | 0.89 | CNR1 (0.46) | CNR1RAD51HTR1ADRD2HTR7 | |
| SCHEMBL6625944 | 0.89 | ALDH1A1 (0.48) | LMNAMAPTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL6623977 | 0.88 | MGAT2 (0.40) | CNR1HTR1ADRD2HTR7MAPT | |
| SCHEMBL6624722 | 0.88 | HTR1A (0.47) | HTR1ADRD2HTR7MAPTSMN1; SMN2 | |
| SCHEMBL6624454 | 0.88 | HTT (0.42) | HTR1ADRD2HTR7MAPTSMN1; SMN2 | |
| SCHEMBL6625246 | 0.88 | HTT (0.49) | CNR1RAD51LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6629939 | 0.86 | MAPT (0.50) | LMNAMAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL6628156 | 0.86 | NPC1 (0.42) | CNR1HTR1ADRD2HTR7MAPT | |
| SCHEMBL6626671 | 0.85 | RAD51 (0.47) | RAD51HTR1ADRD2HTR7MAPT | |
| SCHEMBL6625449 | 0.85 | MAPT (0.47) | MAPTSMN1; SMN2HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373219-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002081453-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER SA (FR) | 2002-10-17 | — | — | WO | disclosed |