Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382647 | 0.81 | GPR17 (0.52) | GPR17KDM4EALDH1A1PARP1EGFR | |
| SCHEMBL6624875 | 0.80 | KDM4E (0.68) | KDM4EALDH1A1PPARGEGFRSRC | |
| SCHEMBL6625739 | 0.79 | GPR17 (0.45) | GPR17KDM4EALDH1A1PPARGMAPT | |
| SCHEMBL6922496 | 0.77 | PPARG (0.50) | GPR17KDM4EALDH1A1PPARGEGFR | |
| SCHEMBL2490337 | 0.77 | KDM4E (0.63) | KDM4EALDH1A1PARP1MAPTPIM1 | |
| SCHEMBL27471919 | 0.75 | PPARG (0.46) | GPR17KDM4EALDH1A1PARP1PPARG | |
| SCHEMBL26135122 | 0.72 | PPARG (0.49) | GPR17KDM4EALDH1A1PPARGEGFR | |
| SCHEMBL22118406 | 0.72 | APOL1 (0.62) | GPR17KDM4EALDH1A1PPARGEGFR | |
| SCHEMBL7242795 | 0.71 | EGFR (0.68) | KDM4EALDH1A1PPARGEGFRSRC | |
| SCHEMBL22118464 | 0.71 | EGFR (0.62) | GPR17KDM4EALDH1A1PPARGEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |