Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 5/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20265857 | 0.86 | MEN1 (0.38) | TDP1ALDH1A1MAPTADORA3MAOA | |
| SCHEMBL8852094 | 0.77 | IDO1 (0.57) | TDP1ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL30366540 | 0.77 | HPRT1 (0.46) | TDP1ALDH1A1MAPTL3MBTL1SLC6A4 | |
| SCHEMBL6562728 | 0.77 | HPRT1 (0.46) | TDP1ALDH1A1MAPTL3MBTL1SLC6A4 | |
| Hydrochloric Acid SCHEMBL27680798 | 0.76 | IDO1 (0.55) | TDP1ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL27641339 | 0.74 | IDO1 (0.48) | TDP1ALDH1A1MAPTADORA3MAOA | |
| SCHEMBL14048610 | 0.74 | MEN1 (0.65) | TDP1ALDH1A1MAPTPTGS1POLB | |
| SCHEMBL6631371 | 0.73 | CYP1A2 (0.59) | TDP1ALDH1A1MAPTADORA3MAOA | |
| SCHEMBL2478233 | 0.73 | CYP2A6 (0.59) | TDP1ALDH1A1MAPTADORA3MAOA | |
| SCHEMBL6630536 | 0.73 | RXFP1 (0.53) | TDP1ALDH1A1MAPTADORA3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894799-B1 | INDOLOMORPHINANE DERIVATIVES AND REMEDIES/PREVENTIVES FOR CEREBRAL DISORDERS | TORAY INDUSTRIES (JP) | 2004-04-07 | — | — | EP | disclosed |
| CN-1117754-C | Indolomorphinane derivatives and remedies/preventives for cerebral disorders | TORAY INDUSTRIES (JP) | 2003-08-13 | — | — | CN | disclosed |
| US-6156762-A | Indolomorphinan derivative and agent for curing and preventing cerebral disorder | TORAY INDUSTRIES, INC. (JP) | 2000-12-05 | — | — | US | disclosed |
| CN-1220668-A | INDOLOMORPHINANE DERIVATIVES AND REMEDIES/PREVENTIVES FOR CEREBRAL DISORDERS | TORAY INDUSTRIES (JP) | 1999-06-23 | — | — | CN | disclosed |
| EP-0894799-A1 | INDOLOMORPHINANE DERIVATIVES AND REMEDIES/PREVENTIVES FOR CEREBRAL DISORDERS | TORAY INDUSTRIES, INC. (JP) | 1999-02-03 | — | — | EP | disclosed |