Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466432 | 0.84 | KMT2A (0.47) | KMT2AMTNR1AMEN1TSHRLMNA | |
| SCHEMBL17559114 | 0.84 | MTNR1A (0.54) | KMT2AMTNR1AMEN1TSHRLMNA | |
| SCHEMBL27483252 | 0.84 | KMT2A (0.47) | KMT2AMTNR1AMEN1TSHRLMNA | |
| SCHEMBL5965355 | 0.81 | KMT2A (0.51) | KMT2AMTNR1AMEN1TSHRACE | |
| SCHEMBL5965361 | 0.81 | KMT2A (0.51) | KMT2AMTNR1AMEN1TSHRACE | |
| SCHEMBL27548369 | 0.81 | KMT2A (0.51) | KMT2AMTNR1AMEN1TSHRLMNA | |
| SCHEMBL8905911 | 0.77 | KMT2A (0.47) | KMT2AMTNR1AMEN1TSHRACE | |
| SCHEMBL6193812 | 0.76 | POLB (0.52) | KMT2AMEN1TSHRPOLBACE | |
| SCHEMBL29443080 | 0.76 | KMT2A (0.46) | KMT2AMEN1ACE | |
| SCHEMBL21490396 | 0.76 | KMT2A (0.46) | KMT2AMEN1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432701-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003031436-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI S.A. (CH) | 2003-04-17 | — | — | WO | disclosed |