Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.75 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CCND1 | P24385 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615812 | 0.86 | SLC6A2 (1.00) | SLC6A2 | |
| SCHEMBL6624855 | 0.80 | SLC6A2 (0.50) | SLC6A2HTR2AHTR2CCDK4CCND1 | |
| SCHEMBL6625147 | 0.80 | SLC6A2 (0.51) | SLC6A2HTR2AHTR2C | |
| SCHEMBL3365470 | 0.79 | SLC6A2 (0.58) | SLC6A2HTR2AHTR2CCDK4CCND1 | |
| Maleic Acid SCHEMBL7619568 | 0.79 | SLC6A2 (0.77) | SLC6A2 | |
| Fumaric Acid SCHEMBL7619574 | 0.79 | SLC6A2 (0.77) | SLC6A2 | |
| SCHEMBL4102885 | 0.74 | SLC6A2 (0.49) | SLC6A2HTR2AHTR2CNOTUMALDH1A1 | |
| SCHEMBL6005012 | 0.72 | SLC6A2 (0.50) | SLC6A2HTR2AHTR2CCDK4CCND1 | |
| SCHEMBL6006493 | 0.72 | SLC6A2 (0.50) | SLC6A2HTR2AHTR2CCDK4CCND1 | |
| SCHEMBL13037083 | 0.71 | SLC6A2 (0.49) | SLC6A2HTR2AHTR2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |