Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | MAT2A | P31153 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625810 | 0.80 | SLC6A2 (0.75) | SLC6A2HTR2AHTR2C | |
| SCHEMBL6623547 | 0.80 | SLC6A2 (0.51) | SLC6A2HTR2AHTR2CSLC6A4OXER1 | |
| SCHEMBL27777665 | 0.76 | OXER1 (0.41) | SLC6A2HTR2AHTR2CSLC6A4OXER1 | |
| SCHEMBL6624825 | 0.71 | KMO (0.41) | SLC6A2KDM4EOXER1CYP2A6PRMT5 | |
| SCHEMBL4557834 | 0.68 | BIRC5 (0.62) | SLC6A2HTR2AHTR2CSLC6A4KDM4E | |
| SCHEMBL27756748 | 0.67 | OXER1 (0.41) | SLC6A2HTR2AHTR2CSLC6A4KDM4E | |
| SCHEMBL7610158 | 0.67 | SLC6A2 (1.00) | SLC6A2 | |
| SCHEMBL1092569 | 0.66 | PRKCI (0.59) | SLC6A2HTR2AHTR2COXER1CYP2A6 | |
| SCHEMBL6629489 | 0.66 | KMO (0.41) | SLC6A2HTR2AHTR2CSLC6A4KDM4E | |
| SCHEMBL6824300 | 0.66 | APP (0.55) | HTR2AHTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |