Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.50 |
| ▸ | CDK4 | P11802 | 4/20 | 0.42 |
| ▸ | CCND1 | P24385 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625810 | 0.80 | SLC6A2 (0.75) | SLC6A2CDK4CCND1ALDH1A1HTR2A | |
| SCHEMBL6624825 | 0.78 | KMO (0.41) | SLC6A2RAB9AALDH1A1HPGD | |
| SCHEMBL3365470 | 0.74 | SLC6A2 (0.58) | SLC6A2CDK4CCND1HTR2AHTR2C | |
| SCHEMBL27756891 | 0.73 | LMNA (0.43) | SLC6A2KMT2ATSHRRAB9AL3MBTL1 | |
| SCHEMBL6624272 | 0.73 | HTR2A (0.41) | SLC6A2ALDH1A1HPGDHTTHTR6 | |
| SCHEMBL6624568 | 0.73 | NOTUM (0.44) | TSHRALDH1A1LMNAHPGDHTT | |
| SCHEMBL6626421 | 0.72 | HTR6 (0.39) | L3MBTL1ALDH1A1HPGDHTTHTR6 | |
| SCHEMBL6626210 | 0.70 | HTR6 (0.43) | SLC6A2TSHRLMNAHPGDHTR6 | |
| SCHEMBL4102885 | 0.69 | SLC6A2 (0.49) | SLC6A2KMT2ATSHRRAB9AL3MBTL1 | |
| SCHEMBL6002347 | 0.67 | SLC6A2 (0.40) | SLC6A2CDK4CCND1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |