Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 6/20 | 0.43 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18362160 | 0.79 | HTR6 (0.48) | HTR6CYP1A2CYP2C9CYP2C19PPARG | |
| SCHEMBL6625102 | 0.78 | HTR2C (0.49) | HTR6ALDH1A1 | |
| SCHEMBL8459745 | 0.78 | CYP1A2 (0.42) | HTR1BHTR6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19089432 | 0.75 | RHEB (0.50) | HTR1BHTR6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20655557 | 0.73 | HTR6 (0.46) | HTR6PPARGPPARAMCHR1PPARD | |
| SCHEMBL18069184 | 0.73 | HTR6 (0.69) | HTR6CYP1A2CYP2C9CYP2C19PPARG | |
| SCHEMBL30503960 | 0.73 | CYP2C9 (0.59) | HTR1BCYP1A2CYP2C9CYP2C19HTR1D | |
| SCHEMBL2924471 | 0.73 | CYP2C9 (0.59) | HTR1BCYP1A2CYP2C9CYP2C19HTR1D | |
| SCHEMBL20655543 | 0.71 | GRM2 (0.42) | HTR1BHTR6CYP2C9HTR1DPPARG | |
| SCHEMBL18361827 | 0.71 | LOXL2 (0.53) | HTR1BHTR6CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |