Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.50 |
| ▸ | LAP3 | P28838 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626581 | 1.00 | CSNK1E (0.50) | CSNK1ELAP3SLC6A2TAAR1ANPEP | |
| SCHEMBL6344357 | 1.00 | CSNK1E (0.50) | CSNK1ELAP3SLC6A2TAAR1ANPEP | |
| SCHEMBL6626571 | 1.00 | CSNK1E (0.50) | CSNK1ELAP3SLC6A2TAAR1ANPEP | |
| Trifluoroacetic Acid SCHEMBL6341911 | 0.91 | CSNK1E (0.43) | CSNK1ELAP3ANPEPRNPEPDNPEP | |
| SCHEMBL6345558 | 0.79 | CSNK1E (0.72) | CSNK1ELAP3SLC6A2TAAR1ANPEP | |
| SCHEMBL6350695 | 0.78 | CSNK1E (0.56) | CSNK1ELAP3SLC6A2TAAR1ANPEP | |
| SCHEMBL6445044 | 0.77 | EPHX1 (0.58) | CSNK1ELAP3SLC6A2TAAR1ANPEP | |
| SCHEMBL6929688 | 0.77 | EPHX1 (0.58) | CSNK1ELAP3SLC6A2TAAR1ANPEP | |
| SCHEMBL6446370 | 0.77 | EPHX1 (0.58) | CSNK1ELAP3SLC6A2TAAR1ANPEP | |
| SCHEMBL9740410 | 0.77 | EPHX1 (0.58) | CSNK1ELAP3SLC6A2TAAR1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395251-A2 | AMINEDIOLS AS AGENTS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002100818-A2 | AMINEDIOLS AS AGENTS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |