Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036111 | 0.81 | LCK (0.42) | LCK | |
| SCHEMBL7983005 | 0.80 | LCK (0.50) | LCK | |
| SCHEMBL7983561 | 0.77 | LCK (0.47) | LCK | |
| SCHEMBL7984051 | 0.77 | LCK (0.45) | LCK | |
| SCHEMBL4042434 | 0.76 | LCK (0.41) | LCK | |
| SCHEMBL8469801 | 0.76 | LCK (0.50) | LCK | |
| SCHEMBL7969763 | 0.76 | LCK (0.53) | LCK | |
| SCHEMBL4037168 | 0.76 | MEN1 (0.44) | LCK | |
| SCHEMBL4038275 | 0.75 | LCK (0.40) | LCK | |
| SCHEMBL4042263 | 0.75 | LCK (0.47) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066286-A4 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2004-02-11 | — | — | EP | disclosed |
| EP-1066286-A1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999045009-A1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-09-10 | — | — | WO | disclosed |