Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861091 | 0.81 | GAA (0.52) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL10674595 | 0.73 | GAA (0.50) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL1981808 | 0.72 | TSHR (0.68) | GAAMGAMSIMGAM2L3MBTL1 | |
| Succinic Acid Diethyl Ester SCHEMBL22780 | 0.72 | GAA (0.67) | GAAMGAMSIMGAM2L3MBTL1 | |
| Succinic Acid Diethyl Ester SCHEMBL27768067 | 0.72 | GAA (0.67) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL28175435 | 0.71 | ESRRB (0.41) | L3MBTL1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL774101 | 0.71 | TSHR (0.43) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL1878449 | 0.71 | TSHR (0.43) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL186433 | 0.71 | TSHR (0.43) | GAAMGAMSIMGAM2KMT2A | |
| Methyl 2-Methylbutanoate SCHEMBL29659730 | 0.71 | GAA (0.48) | GAAMGAMSIMGAM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | disclosed |