SCHEMBL186433

SCHEMBL186433

COC(=O)CC(C)C(=O)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
MGAM O43451 2/20 0.40
GAA P10253 2/20 0.40
SI P14410 2/20 0.40
MGAM2 Q2M2H8 2/20 0.40
HSD17B10 Q99714 1/20 0.40
ESRRB O95718 1/20 0.40
CA14 Q9ULX7 3/20 0.38
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
CA12 O43570 2/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
KMT2A Q03164 2/20 0.34
TET2 Q6N021 1/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1878449 1.00 TSHR (0.43) TSHRSMN1; SMN2MGAMGAASI
SCHEMBL774101 1.00 TSHR (0.43) TSHRSMN1; SMN2MGAMGAASI
SCHEMBL5015120 0.84 GAA (0.46) TSHRMGAMGAASIMGAM2
SCHEMBL6861091 0.84 GAA (0.52) TSHRSMN1; SMN2MGAMGAASI
SCHEMBL16653821 0.84 TSHR (0.39) TSHRSMN1; SMN2MGAMGAASI
SCHEMBL22356272 0.82 TSHR (0.37) TSHRSMN1; SMN2MGAMGAASI
SCHEMBL7864852 0.82 TSHR (0.37) TSHRSMN1; SMN2MGAMGAASI
Itaconate SCHEMBL186812 0.82 ALOX15 (0.43) TSHRHSD17B10ESRRBTET2
SCHEMBL12526876 0.81 CA1 (0.37) SMN1; SMN2MGAMGAASIMGAM2
SCHEMBL3944461 0.81 CYP2D6 (0.47) SMN1; SMN2ESRRBCA14CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 562 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12365782-B2 Compositions and methods for the degradation of waste polypropylene NOVOLOOP, INC. (US) 2025-07-22 US claimed
CN-115210310-B Compositions and methods for waste polypropylene degradation 诺弗洛普有限公司 2024-08-30 CN claimed
US-20240092994-A1 COMPOSITIONS AND METHODS FOR THE DEGRADATION OF WASTE POLYPROPYLENE NOVOLOOP INC (US) 2024-03-21 US claimed
CN-117417796-A Degreasing cleaning agent and application thereof 南京诚志清洁能源有限公司 2024-01-19 CN claimed
CN-115710538-B Self-emulsifying cleaning material and preparation method and application thereof 国网上海市电力公司 2024-01-19 CN claimed
US-11840610-B2 Compositions and methods for the degradation of waste polypropylene NOVOLOOP, INC. (US) 2023-12-12 US claimed
CN-116440031-B Hair care essential oil and preparation method thereof 浙江浩迈科技有限公司 2023-11-10 CN claimed
CN-116462850-B Organosilicon polymer and preparation method and application thereof 融汇智造科技(广州)有限公司 2023-10-20 CN claimed
CN-116143998-A Bio-based hydroxyl-terminated hyperbranched polyester, preparation method thereof and application thereof as plasticizer 上海交通大学 2023-05-23 CN claimed
CN-115710538-A Self-emulsifying cleaning material and preparation method and application thereof 国网上海市电力公司 2023-02-24 CN claimed
US-20210331145-A1 HYDROGENATION PROCESS COMPRISING A CATALYST PREPARED BY ADDITION OF AN ORGANIC COMPOUND IN THE GAS PHASE IFP Energies Nouvelles (FR) 2021-10-28 US claimed
CN-113242766-A Hydrogenation process comprising a catalyst prepared by adding an organic compound in the gas phase IFP 新能源公司 2021-08-10 CN claimed
EP-2479831-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ube Industries, Ltd. (JP) 2012-07-25 EP claimed
US-20120171581-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES, LTD. (JP) 2012-07-05 US claimed
US-6415614-B1 CONTROLLING VAPOR PRESSURE OF MIXTURE VISTEON GLOBAL TECHNOLOGIES, INC. 2002-07-09 US claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US claimed
US-5563290-A Method for preparing optically active succinic acid compound NIPPON OIL CO. LTD. (JP) 1996-10-08 US claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
US-4554374-A CATALYTIC ALKOXYCARBONYLATION TEXACO INC. (US) 1985-11-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120171581-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME SLC8A1, OR10J3, SLC8B1 TSHR 3669/4885SMN1; SMN2 4063/4885MGAM 4087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.