SCHEMBL774101

SCHEMBL774101

COC(=O)C[C@@H](C)C(=O)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
MGAM O43451 2/20 0.40
GAA P10253 2/20 0.40
SI P14410 2/20 0.40
MGAM2 Q2M2H8 2/20 0.40
HSD17B10 Q99714 1/20 0.40
ESRRB O95718 1/20 0.40
CA14 Q9ULX7 3/20 0.38
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
CA12 O43570 2/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
KMT2A Q03164 2/20 0.34
TET2 Q6N021 1/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL186433 1.00 TSHR (0.43) TSHRSMN1; SMN2MGAMGAASI
SCHEMBL1878449 1.00 TSHR (0.43) TSHRSMN1; SMN2MGAMGAASI
SCHEMBL5015120 0.84 GAA (0.46) TSHRMGAMGAASIMGAM2
SCHEMBL6861091 0.84 GAA (0.52) TSHRSMN1; SMN2MGAMGAASI
SCHEMBL16653821 0.84 TSHR (0.39) TSHRSMN1; SMN2MGAMGAASI
SCHEMBL22356272 0.82 TSHR (0.37) TSHRSMN1; SMN2MGAMGAASI
SCHEMBL7864852 0.82 TSHR (0.37) TSHRSMN1; SMN2MGAMGAASI
Itaconate SCHEMBL186812 0.82 ALOX15 (0.43) TSHRHSD17B10ESRRBTET2
SCHEMBL12526876 0.81 CA1 (0.37) SMN1; SMN2MGAMGAASIMGAM2
SCHEMBL3944461 0.81 CYP2D6 (0.47) SMN1; SMN2ESRRBCA14CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119842643-A Alkene reductase mutant and application thereof in synthesis of (R) -2-methyl succinic acid dimethyl ester 中国科学院天津工业生物技术研究所 2025-04-18 CN claimed
CN-120775933-B Application of esterase in synthesis of (R) -3-methyl succinic acid monomethyl ester 中国科学院天津工业生物技术研究所 2025-12-30 CN disclosed
CN-120775933-A Application of esterase in synthesis of (R) -3-methyl succinic acid monomethyl ester 中国科学院天津工业生物技术研究所 2025-10-14 CN disclosed
CN-119842643-B Alkene reductase mutant and application thereof in synthesis of (R) -2-methyl succinic acid dimethyl ester 中国科学院天津工业生物技术研究所 2025-07-15 CN disclosed
CN-119842643-B Alkene reductase mutant and application thereof in synthesis of (R) -2-methyl succinic acid dimethyl ester 中国科学院天津工业生物技术研究所 2025-07-15 CN disclosed
CN-119842643-A Alkene reductase mutant and application thereof in synthesis of (R) -2-methyl succinic acid dimethyl ester 中国科学院天津工业生物技术研究所 2025-04-18 CN disclosed
CN-119842643-A Alkene reductase mutant and application thereof in synthesis of (R) -2-methyl succinic acid dimethyl ester 中国科学院天津工业生物技术研究所 2025-04-18 CN disclosed
CN-119842643-A Alkene reductase mutant and application thereof in synthesis of (R) -2-methyl succinic acid dimethyl ester 中国科学院天津工业生物技术研究所 2025-04-18 CN disclosed
US-20230151401-A1 METHOD OF REDUCING AND RECYCLING OXIDIZED FLAVIN COFACTORS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2023-05-18 US disclosed
CN-111944515-B Circular polarization luminescent material and preparation method and application thereof 中国科学院化学研究所 2022-05-10 CN disclosed
EP-0558630-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1993-09-08 EP disclosed
EP-0558657-A1 RETROVIRAL PROTEASE INHIBITORS. MONSANTO CO (US) 1993-09-08 EP disclosed
EP-0554400-A1 RETROVIRAL PROTEASE INHIBITORS. MONSANTO CO (US) 1993-08-11 EP disclosed
WO-1993001199-A1 CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-01-21 WO disclosed
US-5171892-A Chiral phospholanes via chiral 1,4-diol cyclic sulfates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-15 US disclosed
WO-1992008701-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008700-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008698-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008699-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
EP-0396526-A2 Method of preparing chiral beta-amino acids MONSANTO COMPANY (US) 1990-11-07 EP disclosed