Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | FABP7 | O15540 | 2/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6630038 | 0.70 | HTR2C (0.44) | EPHX2TDP1L3MBTL1 | |
| SCHEMBL8124433 | 0.68 | FABP5 (0.49) | OPRD1FABP7FABP5KMT2AEPHX2 | |
| SCHEMBL31370144 | 0.67 | FABP5 (0.49) | FABP7FABP5ACEKMT2AEPHX2 | |
| SCHEMBL13327272 | 0.67 | L3MBTL1 (0.48) | FABP7FABP5KMT2AEPHX2L3MBTL1 | |
| SCHEMBL3308417 | 0.63 | ACE (0.45) | FABP7FABP5ACEKMT2A | |
| SCHEMBL17356388 | 0.63 | ACE (0.45) | FABP7FABP5ACEKMT2A | |
| SCHEMBL28777376 | 0.63 | ACE (0.45) | FABP7FABP5ACEKMT2A | |
| SCHEMBL22648502 | 0.63 | ACE (0.45) | FABP7FABP5ACEKMT2A | |
| SCHEMBL3310057 | 0.63 | FKBP1A (0.42) | FABP7FABP5FKBP1AACEKMT2A | |
| SCHEMBL16969179 | 0.63 | KMT2A (0.43) | OPRD1FABP7FABP5KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098897-B1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR STIMULATING NEURONAL GROWTH AND ELONGATION | AGOURON PHARMA (US) | 2004-06-09 | — | — | EP | disclosed |
| US-6630472-B1 | Peptidyl-prolyl isomerase inhibitors | PFIZER INC | 2003-10-07 | — | — | US | disclosed |
| EP-1098897-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR STIMULATING NEURONAL GROWTH AND ELONGATION | AGOURON PHARMACEUTICALS, INC. (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004020-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR STIMULATING NEURONAL GROWTH AND ELONGATION | AGOURON PHARMACEUTICALS, INC. (US) | 2000-01-27 | — | — | WO | disclosed |