Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572503 | 0.88 | KDM4E (0.57) | MEN1KMT2AALDH1A1PADI4KDM4E | |
| SCHEMBL29611901 | 0.88 | KMT2A (0.70) | MEN1KMT2AALDH1A1PADI4KDM4E | |
| SCHEMBL19952910 | 0.88 | KMT2A (0.70) | MEN1KMT2AALDH1A1PADI4KDM4E | |
| SCHEMBL9738879 | 0.77 | KDM4E (0.51) | MEN1KMT2AALDH1A1PADI4KDM4E | |
| SCHEMBL29612327 | 0.76 | PADI4 (1.00) | MEN1KMT2AALDH1A1PADI4 | |
| SCHEMBL19953012 | 0.76 | PADI4 (1.00) | MEN1KMT2AALDH1A1PADI4 | |
| SCHEMBL8540248 | 0.76 | KDM4E (0.47) | MEN1KMT2AALDH1A1PADI4KDM4E | |
| SCHEMBL3985154 | 0.76 | KDM4E (0.74) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL29415434 | 0.75 | KDM4E (1.00) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL2805779 | 0.75 | KDM4E (1.00) | MEN1KMT2AALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392677-A2 | CHIRAL BROAD-SPECTRUM ANTIBACTERIAL 7-SUBSTITUTED PIPERIDINO-QUINOLONE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS | Wockhardt Limited (IN) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002085886-A2 | CHIRAL, BROAD-SPECTRUM ANTIBACTERIAL 7-SUBSTITUTED PIPERIDINO-QUINOLONE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS | WOCKHARDT LIMITED (IN) | 2002-10-31 | — | — | WO | disclosed |