Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PADI4 | Q9UM07 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214494 | 0.79 | KDM4E (0.43) | KDM4ETDP1PADI4ALDH1A1NPC1 | |
| SCHEMBL6627007 | 0.77 | MEN1 (0.68) | KDM4ETDP1PADI4MEN1KMT2A | |
| SCHEMBL10572503 | 0.74 | KDM4E (0.57) | KDM4ETDP1PADI4MEN1KMT2A | |
| SCHEMBL8540248 | 0.73 | KDM4E (0.47) | KDM4ETDP1PADI4MEN1KMT2A | |
| SCHEMBL10738884 | 0.70 | KDM4E (0.64) | KDM4ETDP1PADI4MEN1KMT2A | |
| SCHEMBL29415434 | 0.70 | KDM4E (1.00) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL2805779 | 0.70 | KDM4E (1.00) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL1620204 | 0.69 | KDM4E (0.72) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL7811680 | 0.68 | KDM4E (0.70) | KDM4ETDP1PADI4ALDH1A1HPGD | |
| SCHEMBL31298181 | 0.67 | KDM4E (0.74) | KDM4ETDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099032-A | Aminopyrroles formed from hydroxypyrroles by displacement | ABBOTT LABORATORIES (US) | 1992-03-24 | — | — | US | disclosed |