Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PADI4 | Q9UM07 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627007 | 0.76 | MEN1 (0.68) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL10572503 | 0.75 | KDM4E (0.57) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL9738879 | 0.73 | KDM4E (0.51) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL2082993 | 0.70 | KDM4E (0.37) | KDM4EALDH1A1POLB | |
| SCHEMBL14758853 | 0.70 | KCNH2 (0.45) | — | |
| SCHEMBL29611901 | 0.68 | KMT2A (0.70) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL19952910 | 0.68 | KMT2A (0.70) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL3985154 | 0.67 | KDM4E (0.74) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL10738884 | 0.67 | KDM4E (0.64) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL29415434 | 0.67 | KDM4E (1.00) | KDM4ETDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849757-A | Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |