Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | GLS | O94925 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10165065 | 0.87 | LOX (0.48) | L3MBTL1BRD4NAMPTGLSKDM4A | |
| SCHEMBL8226463 | 0.82 | L3MBTL1 (0.44) | L3MBTL1BRD4NAMPTGLSKDM4A | |
| SCHEMBL1698559 | 0.82 | L3MBTL1 (0.47) | L3MBTL1BRD4NAMPTGLSKDM4A | |
| SCHEMBL29693623 | 0.82 | L3MBTL1 (0.47) | L3MBTL1BRD4NAMPTGLSKDM4A | |
| SCHEMBL30400296 | 0.81 | L3MBTL1 (0.43) | L3MBTL1BRD4NAMPTGLSKDM4A | |
| SCHEMBL15871964 | 0.81 | BRD4 (0.49) | L3MBTL1BRD4NAMPTGLSKDM4A | |
| SCHEMBL30399922 | 0.81 | L3MBTL1 (0.49) | L3MBTL1BRD4NAMPTGLSKDM4A | |
| SCHEMBL10163771 | 0.81 | L3MBTL1 (0.49) | L3MBTL1BRD4NAMPTGLSKDM4A | |
| SCHEMBL18049277 | 0.81 | LOXL2 (0.60) | L3MBTL1BRD4NAMPTHDAC1CYP3A4 | |
| SCHEMBL30931637 | 0.81 | EPHX2 (0.44) | L3MBTL1BRD4NAMPTGLSKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392680-A2 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090352-A2 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-11-14 | — | — | WO | disclosed |