Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828432 | 0.81 | HIF1A (0.44) | HIF1ATSHRRAB9ACYP3A4CYP2D6 | |
| SCHEMBL7101382 | 0.81 | HIF1A (0.44) | HIF1ATSHRRAB9ACYP3A4CYP2D6 | |
| SCHEMBL2866788 | 0.80 | HIF1A (0.49) | HIF1AKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL29673995 | 0.80 | HIF1A (0.49) | HIF1AKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL22326129 | 0.80 | HIF1A (0.49) | HIF1AKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL31349879 | 0.80 | HIF1A (0.49) | HIF1AKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL18420 | 0.80 | HIF1A (0.49) | HIF1AKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL54336 | 0.80 | HIF1A (0.49) | HIF1AKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL2890313 | 0.78 | HIF1A (0.51) | HIF1AKMT2AMEN1MAPTKDM4E | |
| SCHEMBL2890312 | 0.78 | HIF1A (0.51) | HIF1AKMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395117-A1 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES IN THE PROTECTION OF MATERIALS | Bayer Chemicals AG (DE) | 2004-03-10 | — | — | EP | disclosed |
| EP-1335909-A1 | 3-NITROISOXAZOLES AND THEIR USE IN THE PROTECTION OF MATERIALS | Bayer Aktiengesellschaft (DE) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002094020-A1 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES IN THE PROTECTION OF MATERIALS | BAYER CHEMICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |
| WO-2002034731-A1 | 3-NITROISOXAZOLES AND THEIR USE IN THE PROTECTION OF MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-02 | — | — | WO | disclosed |