Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890313 | 1.00 | HIF1A (0.51) | HIF1AKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL27038477 | 0.91 | HIF1A (0.61) | HIF1AKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL8423691 | 0.91 | HIF1A (0.61) | HIF1AKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL9023766 | 0.86 | HIF1A (0.47) | HIF1AKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL8357978 | 0.86 | HIF1A (0.38) | HIF1AKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL8760920 | 0.82 | HIF1A (0.44) | HIF1AKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL3661940 | 0.81 | HIF1A (0.51) | HIF1AKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL321897 | 0.81 | HIF1A (0.45) | HIF1AMAPTMAOB | |
| SCHEMBL483559 | 0.81 | HIF1A (0.52) | HIF1AKMT2AMEN1 | |
| SCHEMBL828172 | 0.81 | HIF1A (0.52) | HIF1AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9629367-B2 | Active compound combinations containing a thiazoylisoxazoline and a fungicide | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-04-25 | — | — | US | disclosed |
| US-20150327549-A1 | ACTIVE COMPOUND COMBINATIONS CONTAINING A THIAZOYLISOXAZOLINE AND A FUNGICIDE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-11-19 | — | — | US | disclosed |
| EP-2911513-A1 | COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE | Bayer Cropscience LP (US) | 2015-09-02 | — | — | EP | disclosed |
| WO-2014066877-A1 | COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE | BAYER CROPSCIENCE LP (US) | 2014-05-01 | — | — | WO | disclosed |
| EP-2699093-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND | Bayer Intellectual Property GmbH (DE) | 2014-02-26 | — | — | EP | disclosed |
| US-8410157-B2 | Fungicidal N-cycloalkyl-benzyl-thiocarboxamides or N-cycloalkyl-benzyl-N′-substituted-amidine derivatives | BAYER CROPSCIENCE AG (DE) | 2013-04-02 | — | — | US | disclosed |
| US-8309592-B2 | — | — | 2012-11-13 | — | — | US | disclosed |
| WO-2012143127-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND | BAYER CROPSCIENCES AG (DE) | 2012-10-26 | — | — | WO | disclosed |
| US-20100144817-A1 | FUNGICIDEL N-CYCLOALKYL-BENZYL-THIOCARBOXAMIDES OR N-CYCLOALKYL-BENZYL-N'-SUBSTITUTED-AMIDINE DERIVATIVES | BAYER SAS (FR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150327549-A1 | ACTIVE COMPOUND COMBINATIONS CONTAINING A THIAZOYLISOXAZOLINE AND A FUNGICIDE | CYP4X1, BROX, PRDX5 | HIF1A 3838/4885KMT2A 2591/4885KDM4E 2472/4885 |
| US-20100144817-A1 | FUNGICIDEL N-CYCLOALKYL-BENZYL-THIOCARBOXAMIDES OR N-CYCLOALKYL-BENZYL-N'-SUBSTITUTED-AMIDINE DERIVATIVES | CBR3, NRDC, NAT1 | HIF1A 4619/4885KMT2A 2852/4885KDM4E 3314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.