Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815749 | 0.75 | CYP3A4 (0.47) | AHRMAPTCYP3A4HTR6ALDH1A1 | |
| SCHEMBL29420757 | 0.73 | AHR (1.00) | AHRMAPTCYP3A4HTR6ALDH1A1 | |
| SCHEMBL154593 | 0.73 | AHR (1.00) | AHRMAPTCYP3A4HTR6ALDH1A1 | |
| Carbazole SCHEMBL27967060 | 0.72 | ALDH1A1 (0.78) | AHRMAPTCYP3A4ALDH1A1HSD17B10 | |
| 2-Methyl Gramine SCHEMBL2519973 | 0.72 | MAPT (1.00) | AHRMAPTCYP3A4HTR6ALDH1A1 | |
| SCHEMBL10773081 | 0.72 | KDM4E (0.56) | MAPTALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL1757631 | 0.71 | AHR (0.64) | AHRMAPTCYP3A4HTR6ALDH1A1 | |
| SCHEMBL3092111 | 0.71 | AHR (0.69) | AHRMAPTCYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL8327130 | 0.71 | AURKA (0.44) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL4855172 | 0.70 | AHR (0.61) | AHRMAPTCYP3A4HTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109652817-A | A kind of small Generator for sodium hypochlorite for sewage treatment | 辽宁中舟得水环保科技有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-104725320-A | Sulfitonetaine sterilizing agent and synthetic method thereof | UNIV SOUTHWEST PETROLEUM | 2015-06-24 | — | — | CN | claimed |
| CN-101011061-A | Biological antistain agent with low surface energy characteristic and its preparing process | CSIC NO 725 RES & DEV I (CN) | 2007-08-08 | — | — | CN | claimed |
| CN-1233630-C | N-substituted indole derivative preparation method | OCEAN UNIV CHINA (CN) | 2005-12-28 | — | — | CN | claimed |
| CN-1544419-A | N-substituted indole derivative preparation method | 中国海洋大学 | 2004-11-10 | — | — | CN | claimed |
| CN-109652817-A | A kind of small Generator for sodium hypochlorite for sewage treatment | 辽宁中舟得水环保科技有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-109225354-A | A kind of preparation method of ternary catalyzing unit cleaning agent | 盘锦洪鼎化工有限公司 | 2019-01-18 | — | — | CN | disclosed |
| CN-103012243-B | A kind of acrylate functional monomer containing gramine structure and preparation method thereof | QINGDAO UNIVERSITY (CN) | 2015-09-09 | — | — | CN | disclosed |
| CN-104725320-A | Sulfitonetaine sterilizing agent and synthetic method thereof | UNIV SOUTHWEST PETROLEUM | 2015-06-24 | — | — | CN | disclosed |
| CN-104725320-A | Sulfitonetaine sterilizing agent and synthetic method thereof | UNIV SOUTHWEST PETROLEUM | 2015-06-24 | — | — | CN | disclosed |
| CN-103012243-A | Acrylic ester functional monomer containing donaxine structure and preparation method thereof | UNIV QINGDAO | 2013-04-03 | — | — | CN | disclosed |
| CN-101011061-A | Biological antistain agent with low surface energy characteristic and its preparing process | CSIC NO 725 RES & DEV I (CN) | 2007-08-08 | — | — | CN | disclosed |
| EP-1135124-A2 | ANTIHYPERTRIGLYCERIDEMIC, ANTIHYPERGLYCEMIC, ANTI-ANGIOGENIC AND WOUND HEALING SUBSTITUDED INDOLEALKANOIC ACIDS | The Institutes for Pharmaceutical Discovery, Inc. (US) | 2001-09-26 | — | — | EP | disclosed |
| WO-2001064205-A2 | COMPOSITIONS CONTAINING A SUBSTITUTED INDOLEALKANOIC ACID AND AN ANGIOTENSIN CONVERTING ENZYME INHIBITOR | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2001-09-07 | — | — | WO | disclosed |
| WO-2001051489-A2 | METHODS FOR LOWERING URIC ACID LEVELS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2001-07-19 | — | — | WO | disclosed |
| EP-1066283-A2 | SUBSTITUTED INDOLEALKANOIC ACIDS | The Institutes for Pharmaceutical Discovery, Inc. (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-2000032180-A2 | ANTIHYPERTRIGLYCERIDEMIC, ANTIHYPERGLYCEMIC, ANTI-ANGIOGENIC AND WOUND HEALING SUBSTITUTED INDOLEALKANOIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, INC. (US) | 2000-06-08 | — | — | WO | disclosed |
| CN-1053188-C | Quinolizinone type compounds | ABBOTT LAB (US) | 2000-06-07 | — | — | CN | disclosed |
| WO-1999050268-A2 | SUBSTITUTED INDOLEALKANOIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, INC. (US) | 1999-10-07 | — | — | WO | disclosed |
| CN-1137273-A | Quinolizinone type compounds | ABBOTT LAB (US) | 1996-12-04 | — | — | CN | disclosed |