Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21575096 | 0.81 | NPC1 (0.38) | NPC1RAB9AKMT2ACES2CES1 | |
| SCHEMBL23516375 | 0.79 | PLA2G2A (0.54) | KMT2A | |
| SCHEMBL6624366 | 0.76 | HDAC3 (0.43) | NPC1RAB9ASLC22A6HDAC3HDAC4 | |
| SCHEMBL6626651 | 0.74 | SLC22A6 (0.44) | NPC1RAB9ASLC22A6HDAC3HDAC4 | |
| SCHEMBL29009735 | 0.74 | FFAR4 (0.47) | SLC22A6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5080184 | 0.74 | HDAC3 (0.55) | NPC1RAB9AHDAC3HDAC4HDAC1 | |
| SCHEMBL30428306 | 0.73 | F13A1 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6629691 | 0.73 | HDAC3 (0.48) | NPC1RAB9ASLC22A6HDAC3HDAC4 | |
| SCHEMBL5078142 | 0.73 | CES2 (0.53) | NPC1RAB9ASLC22A6HDAC3HDAC4 | |
| SCHEMBL31661689 | 0.73 | CES2 (0.53) | NPC1RAB9ASLC22A6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167348-A | Parasitic pest expellent and its application method using pyridinone compounds as effective component | 三井化学AGRO株式会社 | 2019-08-23 | — | — | CN | disclosed |
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |