Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.43 |
| ▸ | CTSL | P07711 | 5/20 | 0.40 |
| ▸ | CTSS | P25774 | 5/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5105882 | 0.91 | CTSK (0.41) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5096573 | 0.87 | EPHX2 (0.42) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5092584 | 0.87 | CTSK (0.47) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4766701 | 0.86 | MEN1 (0.43) | CTSKCTSLCTSSCTSBMEN1 | |
| SCHEMBL7427478 | 0.86 | MEN1 (0.43) | CTSKCTSLCTSSCTSBMEN1 | |
| SCHEMBL5093139 | 0.86 | KMT2A (0.45) | CTSKTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL7434825 | 0.86 | KMT2A (0.45) | CTSKTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL4686403 | 0.86 | CTSK (0.54) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7431349 | 0.85 | KMT2A (0.45) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5096578 | 0.85 | POLB (0.48) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1384713-A1 | 4-amino-azepan-3-one derivatives as protease inhibitors | SmithKline Beecham Corporation (US) | 2004-01-28 | — | — | EP | disclosed |