⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28216984 | 0.79 | — | — | |
| SCHEMBL13465078 | 0.75 | — | — | |
| SCHEMBL10076030 | 0.75 | — | — | |
| SCHEMBL21693847 | 0.71 | — | — | |
| SCHEMBL6788884 | 0.71 | MAPK1 (0.33) | — | |
| SCHEMBL10146209 | 0.71 | MAPK1 (0.38) | — | |
| SCHEMBL29180235 | 0.71 | MAPK1 (0.33) | — | |
| SCHEMBL29180234 | 0.71 | MAPK1 (0.33) | — | |
| SCHEMBL29049964 | 0.71 | LMNA (0.40) | — | |
| SCHEMBL13865299 | 0.70 | MAPK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10882843-B2 | 5-aminopyrazole carboxamide derivative as BTK inhibitor and preparation method and pharmaceutical composition thereof | Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) | 2021-01-05 | — | — | US | disclosed |
| US-20190152952-A1 | 5-AMINOPYRAZOLE CARBOXAMIDE DERIVATIVE AS BTK INHIBITOR AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | Evopoint Biosciences Co., Ltd. (CN) | 2019-05-23 | — | — | US | disclosed |
| CN-1315888-C | Polymer containing methyl methacrylate as main component | CHI MEI CORP (CN) | 2007-05-16 | — | — | CN | disclosed |
| CN-1752118-A | Polymer containing methyl methacrylate as main component | QIMEI IND CO LTD (CN) | 2006-03-29 | — | — | CN | disclosed |
| EP-0974602-B1 | Catalyst and process for hydrogenating olefinically unsaturated compound | JSR CORP (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-6291596-B1 | CONTACTING OLEFINICALLY UNSATURATED COMPOUND WITH HYDROGEN IN THE PRESENCE OF A HYDROGENATION CATALYST COMPRISING TITANIUM OR ZIRCONIUM OR HAFNIUM COMPOUND IN AN INERT, ORGANIC SOLVENT | JSR CORPORATION (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-0974602-A1 | Catalyst and process for hydrogenating olefinically unsaturated compound | JSR Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |