Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11286678 | 0.99 | KDM4E (0.50) | KDM4EALDH1A1CYP2D6CYP1A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL28918885 | 0.79 | NPBWR1 (0.55) | KDM4EALDH1A1LMNAPABPC1MEN1 | |
| SCHEMBL24446594 | 0.79 | CYP2D6 (0.74) | KDM4EALDH1A1CYP2D6CYP1A2SLC6A4 | |
| SCHEMBL30080216 | 0.79 | CYP2D6 (0.74) | KDM4EALDH1A1CYP2D6CYP1A2SLC6A4 | |
| SCHEMBL11846315 | 0.79 | PABPC1 (0.58) | KDM4EALDH1A1CYP2D6CYP1A2SLC6A4 | |
| SCHEMBL2342350 | 0.79 | CYP2D6 (0.74) | KDM4EALDH1A1CYP2D6CYP1A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL15288851 | 0.79 | HTT (0.49) | KDM4EALDH1A1CYP2D6CYP1A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL10426211 | 0.78 | PABPC1 (0.57) | KDM4EALDH1A1CYP2D6CYP1A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL158567 | 0.78 | CYP3A4 (0.74) | KDM4EALDH1A1CYP2D6CYP1A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL29729337 | 0.78 | CYP3A4 (0.74) | KDM4EALDH1A1CYP2D6CYP1A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138020-B1 | ANTI-ADHESIVE PROPHYLACTICA AND MEDICINES CONTAINING A SECRETOLYTICALLY ACTIVE BENZYLAMINE DERIVATIVE | Dr. Karl Thomae GmbH (DE) | 1992-06-03 | — | — | EP | claimed |
| US-20040259955-A1 | New pharmaceutical compositions containing ambroxol and isopropamide iodide | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-23 | — | — | US | disclosed |
| WO-2004041263-A1 | NEW PHARMACEUTICAL COMPOSITIONS CONTAINING AMBROXOL AND ISOPROPAMIDE IODIDE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-05-21 | — | — | WO | disclosed |
| EP-1417961-A1 | New pharmaceutical compositions containing a combination of ambroxol or bromhexine and isopropamide iodide | Boehringer Ingelheim International GmbH (DE) | 2004-05-12 | — | — | EP | disclosed |
| EP-0061157-A1 | 2-Benzoylamino substituted benzylamine derivative and a process for preparation thereof | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1982-09-29 | — | — | EP | disclosed |