Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628191 | 0.84 | GAA (0.64) | HTTNPSR1ATMRAB9AGAA | |
| SCHEMBL10875758 | 0.75 | RAB9A (0.65) | HTTNPSR1RAB9AGAANPC1 | |
| SCHEMBL3274053 | 0.75 | THRB (0.79) | THRBHTTRAB9AGAANPC1 | |
| SCHEMBL6719393 | 0.72 | TDP1 (0.55) | THRBHTTNPSR1GAATDP1 | |
| SCHEMBL330776 | 0.72 | TDP1 (0.56) | ATMRAB9AGAANPC1HSP90AA1 | |
| SCHEMBL11179333 | 0.72 | NPSR1 (0.58) | THRBHTTNPSR1GAATDP1 | |
| SCHEMBL22173521 | 0.72 | THRB (0.73) | THRBHTTRAB9AGAANPC1 | |
| SCHEMBL27745059 | 0.71 | KMT2A (0.44) | HTTNPSR1ATMRAB9AGAA | |
| Benzamide SCHEMBL28002190 | 0.71 | THRB (0.57) | THRBRAB9ANPC1TDP1KMT2A | |
| SCHEMBL6719138 | 0.71 | KMT2A (0.59) | THRBHTTNPSR1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349860-B1 | SYNTHESES FOR PREPARING 1,4-DIKETOPYRROLO[3,4-C]PYRROLES | SUN CHEMICAL CORP (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-1349860-A2 | SYNTHESES FOR PREPARING 1,4-DIKETOPYRROLO[3,4-C]PYRROLES | SUN CHEMICAL CORPORATION (US) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002068422-A2 | SYNTHESES FOR PREPARING 1,4-DIKETOPYRROLO[3,4-C]PYRROLES | SUN CHEMICAL CORPORATION (US) | 2002-09-06 | — | — | WO | disclosed |
| US-6388093-B1 | REACTING A B-KETOAMIDE WITH A STRONG BASE; HALOGENTAION; CYCLIZATION | SUN CHEMICAL CORPORATION | 2002-05-14 | — | — | US | disclosed |