Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.47 |
| ▸ | CTSL | P07711 | 11/20 | 0.47 |
| ▸ | CTSS | P25774 | 7/20 | 0.47 |
| ▸ | CTSB | P07858 | 6/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PKLR | P30613 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4768241 | 0.83 | CTSK (0.45) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5105578 | 0.81 | CTSK (0.55) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL8336654 | 0.81 | CTSK (0.45) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5105546 | 0.79 | CTSK (0.53) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5105583 | 0.78 | CTSK (0.57) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5105547 | 0.77 | CTSK (0.63) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5092516 | 0.77 | CTSK (0.55) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4921667 | 0.77 | CTSK (0.59) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5099022 | 0.77 | CTSK (0.53) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7541657 | 0.77 | ALDH1A1 (0.42) | CTSKCTSLCTSSPKMPKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |