Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | MAT2A | P31153 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623547 | 0.85 | SLC6A2 (0.51) | OXER1SLC6A2MAT2AHTR2AHTR2C | |
| SCHEMBL6629531 | 0.77 | SLC6A2 (0.46) | CDC7CDK2MAP3K14HTR7SLC6A2 | |
| SCHEMBL6628412 | 0.77 | HTR2C (0.46) | CDC7CDK2ROCK1HTR7SLC6A2 | |
| SCHEMBL6624825 | 0.75 | KMO (0.41) | KMOCDC7CDK2ROCK1MAP3K14 | |
| SCHEMBL24630635 | 0.74 | KCNH2 (0.40) | CDC7CDK2HTR7SLC6A2GAA | |
| SCHEMBL1093444 | 0.74 | CYP2A6 (0.53) | KMOCDC7CDK2ROCK1MAP3K14 | |
| SCHEMBL30277740 | 0.74 | CYP2A6 (0.53) | KMOCDC7CDK2ROCK1MAP3K14 | |
| SCHEMBL6626507 | 0.73 | KDM4E (0.43) | SLC6A2HTR2AHTR2CGAAKDM4E | |
| SCHEMBL3365470 | 0.71 | SLC6A2 (0.58) | SLC6A2HTR2AHTR2CBIRC5 | |
| SCHEMBL24826382 | 0.71 | HTR2A (0.53) | SLC6A2HTR2AHTR2CCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |