Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624855 | 0.78 | SLC6A2 (0.50) | ALDH1A1HPGDRAB9ASLC6A2 | |
| SCHEMBL6629489 | 0.75 | KMO (0.41) | KMOOXER1CYP2A6BIRC5KDM4E | |
| SCHEMBL6625147 | 0.71 | SLC6A2 (0.51) | OXER1CYP2A6KDM4EPRMT5MAT2A | |
| SCHEMBL157573 | 0.70 | BIRC5 (0.62) | KMOOXER1CYP2A6BIRC5KDM4E | |
| SCHEMBL6624568 | 0.69 | NOTUM (0.44) | CYP2A6ALDH1A1POLBHPGDCYP1A2 | |
| SCHEMBL28101302 | 0.68 | HTR6 (0.60) | KMO | |
| SCHEMBL7675986 | 0.67 | SLC6A4 (0.45) | KMOOXER1CYP2A6BIRC5KDM4E | |
| SCHEMBL27777665 | 0.66 | OXER1 (0.41) | KMOOXER1ALDH1A1HSD17B10NPC1 | |
| SCHEMBL30277740 | 0.65 | CYP2A6 (0.53) | KMOOXER1CYP2A6BIRC5CDC7 | |
| SCHEMBL15213127 | 0.65 | CDC7 (0.46) | KMOOXER1CYP2A6BIRC5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |