SCHEMBL66296

SCHEMBL66296

Clc1nc2cccc(Cl)c2[nH]1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 1/20 0.44
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
AHR P35869 1/20 0.42
PARP1 P09874 1/20 0.41
CLK1 P49759 1/20 0.41
CDK9 P50750 1/20 0.41
CDK5 Q00535 1/20 0.41
DYRK1A Q13627 1/20 0.41
DYRK2 Q92630 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
DYRK1B Q9Y463 1/20 0.41
PSMB8 P28062 3/20 0.39
AR P10275 1/20 0.39
KDM4E B2RXH2 2/20 0.39
NPC1 O15118 2/20 0.39
ALDH1A1 P00352 2/20 0.39
RAB9A P51151 2/20 0.39
GPR55 Q9Y2T6 1/20 0.39
ACP1 P24666 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17821369 0.79 NOS1 (0.41) NOS1CA12CA9AHRPARP1
SCHEMBL5924246 0.79 TYMS (0.51) NOS1CA12CA9AHRPARP1
SCHEMBL9502145 0.79 PARP1 (0.59) NOS1CA12CA9AHRPARP1
SCHEMBL9305632 0.79 CA12 (0.40) CA12CA9PARP1KDM4ENPC1
SCHEMBL6139156 0.79 PARP1 (0.41) AHRPARP1ARNPC1ALDH1A1
SCHEMBL24113220 0.79 MEN1 (0.41) NOS1CA12CA9AHRPARP1
SCHEMBL8956424 0.79 TDP1 (0.33) PARP1KDM4ENPC1ALDH1A1RAB9A
SCHEMBL9305473 0.79 ACHE (0.43) PARP1PSMB8ARKDM4EALDH1A1
SCHEMBL20479323 0.79 PDPK1 (0.43) NOS1CA12CA9PARP1CDK9
SCHEMBL22962172 0.75 KDM4E (0.45) NOS1CA12CA9AHRPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126467-A Heat-resistant modified polyvinyl chloride power tube and preparation method thereof 杭州鼎新建科实业有限公司 2024-06-04 CN claimed
CN-117986764-A Flame-retardant modified polyvinyl chloride power tube and preparation method thereof 杭州鼎新建科实业有限公司 2024-05-07 CN claimed
CN-111335033-A Neckerchief fabric for infant care and preparation method thereof 张海军 2020-06-26 CN claimed
US-8188254-B2 C-class oligonucleotide analogs with enhanced immunostimulatory potency COLEY PHARMACEUTICAL GMBH (DE) 2012-05-29 US claimed
CN-101454451-A Class C oligonucleotide analogs with enhanced immunostimulatory capacity COLEY PHARM GMBH (DE) 2009-06-10 CN claimed
EP-1978997-A1 TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS Apollo Life Sciences Limited (AU) 2008-10-15 EP claimed
WO-2007070983-A1 TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS APOLLO LIFE SCIENCES LIMITED (AU) 2007-06-28 WO claimed
EP-1730281-A2 IMMUNOSTIMULATORY NUCLEIC ACIDS FOR INDUCING IL-10 RESPONSES Coley Pharmaceutical Group, Inc. (US) 2006-12-13 EP claimed
EP-1728863-A2 C-class oligonucleotide analogs with enhanced immunostimulatory potency Coley Pharmaceutical GmbH (DE) 2006-12-06 EP claimed
EP-1678303-A2 C-CLASS OLIGONUCLEOTIDE ANALOGS WITH ENHANCED IMMUNOSTIMULATORY POTENCY Coley Pharmaceutical GmbH (DE) 2006-07-12 EP claimed
WO-2005111057-A2 IMMUNOSTIMULATORY NUCLEIC ACIDS FOR INDUCING IL-10 RESPONSES COLEY PHARMACEUTICAL GROUP, INC. (US) 2005-11-24 WO claimed
US-20050239734-A1 C-class oligonucleotide analogs with enhanced immunostimulatory potency COLEY PHARMACEUTICAL GMBH (DE) 2005-10-27 US claimed
EP-1578954-A2 5' CPG NUCLEIC ACIDS AND METHODS OF USE Coley Pharmaceutical Group, Inc. (US) 2005-09-28 EP claimed
WO-2005042018-A2 C-CLASS OLIGONUCLEOTIDE ANALOGS WITH ENHANCED IMMUNOSTIMULATORY POTENCY COLEY PHARMACEUTICAL GMBH (DE) 2005-05-12 WO claimed
US-20040171571-A1 5' CpG nucleic acids and methods of use COLEY PHARMACEUTICAL GROUP, INC. (US) 2004-09-02 US claimed
WO-2004053104-A2 5’ CPG NUCLEIC ACIDS AND METHODS OF USE COLEY PHARMACEUTICAL GROUP, INC. (US) 2004-06-24 WO claimed
CN-1107508-C Process for the preparation of a composition containing 2',5'-oligoadenylic acid derivatives UNIV TEMPLE (US) 2003-05-07 CN claimed
US-12637646-B2 DNA origami cell sensing platform OHIO STATE INNOVATION FOUNDATION (US) 2026-05-26 US disclosed
WO-2004005476-A2 NUCLEIC ACID COMPOSITIONS FOR STIMULATING IMMUNE RESPONSES COLEY PHARMACEUTICAL GROUP, INC. (US) 2004-01-15 WO disclosed
US-4594420-A Substituted with bromine or chlorine HOECHST AKTIENGESELLSCHAFT (DE) 1986-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637646-B2 DNA origami cell sensing platform DNMT3A, EPCAM, CASR NOS1 4227/4885CA12 2049/4885CA9 1746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.