Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 8/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6391582 | 0.82 | CHRNA7 (0.56) | CHRNA7NPC1CHRM4ALDH1A1GAA | |
| SCHEMBL6629447 | 0.82 | HTR3A (0.55) | CHRNA7HTR3A | |
| SCHEMBL6395473 | 0.80 | CHRNA7 (0.59) | CHRNA7NPC1ALDH1A1GAARAB9A | |
| SCHEMBL6390032 | 0.79 | CHRNA7 (0.59) | CHRNA7NPC1RAB9AHTR3A | |
| SCHEMBL6390022 | 0.78 | CHRNA7 (0.64) | CHRNA7NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6390025 | 0.78 | CHRNA7 (0.64) | CHRNA7NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6395388 | 0.78 | CHRNA7 (0.53) | CHRNA7 | |
| SCHEMBL6395384 | 0.78 | CHRNA7 (0.53) | CHRNA7 | |
| SCHEMBL6389756 | 0.77 | CHRNA7 (0.62) | CHRNA7NPC1RAB9AHTR3A | |
| SCHEMBL6392216 | 0.77 | CHRNA7 (0.59) | CHRNA7NPC1CHRM4RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438308-A1 | N-AZABICYCLO-SUBSTITUTED HETERO-BICYCLIC CARBOXAMIDES AS NACHR AGONISTS | PHARMACIA & UPJOHN COMPANY (US) | 2004-07-21 | — | — | EP | claimed |
| WO-2003037896-A1 | N-AZABICYCLO-SUBSTITUTED HETERO-BICYCLIC CARBOXAMIDES AS NACHR AGONISTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-05-08 | — | — | WO | claimed |
| EP-1438308-A1 | N-AZABICYCLO-SUBSTITUTED HETERO-BICYCLIC CARBOXAMIDES AS NACHR AGONISTS | PHARMACIA & UPJOHN COMPANY (US) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003037896-A1 | N-AZABICYCLO-SUBSTITUTED HETERO-BICYCLIC CARBOXAMIDES AS NACHR AGONISTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-05-08 | — | — | WO | disclosed |