Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21768099 | 0.83 | KMT2A (0.76) | MAPK14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29941957 | 0.82 | MAPK14 (1.00) | MAPK14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL166484 | 0.80 | LMNA (0.82) | MAPK14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL243238 | 0.79 | SMN1; SMN2 (0.63) | MAPK14MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27843329 | 0.79 | LMNA (0.80) | MAPK14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4893253 | 0.79 | NPC1 (0.71) | MAPK14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5650532 | 0.78 | KMT2A (0.65) | MAPK14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1393086 | 0.78 | LMNA (1.00) | MAPK14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL21768049 | 0.76 | LMNA (0.76) | MAPK14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7654965 | 0.76 | KMT2A (0.65) | MAPK14MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458374-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051841-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |