Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.55 |
| ▸ | CTSL | P07711 | 12/20 | 0.52 |
| ▸ | CTSS | P25774 | 8/20 | 0.52 |
| ▸ | CTSB | P07858 | 3/20 | 0.52 |
| ▸ | CTSV | O60911 | 2/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6630006 | 1.00 | CTSK (0.55) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6630009 | 1.00 | CTSK (0.55) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5092508 | 0.88 | CTSK (0.60) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5092490 | 0.88 | CTSK (0.60) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4317853 | 0.88 | TAS1R3 (0.62) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5949040 | 0.88 | TAS1R3 (0.62) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4317862 | 0.88 | TAS1R3 (0.62) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4323042 | 0.88 | TAS1R3 (0.62) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4317857 | 0.88 | TAS1R3 (0.62) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6764484 | 0.84 | CTSK (0.67) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |