Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.82 |
| ▸ | CTSL | P07711 | 16/20 | 0.82 |
| ▸ | CTSS | P25774 | 16/20 | 0.82 |
| ▸ | CTSB | P07858 | 6/20 | 0.82 |
| ▸ | CTSV | O60911 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4791582 | 0.90 | CTSK (1.00) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7445941 | 0.88 | CTSK (0.96) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6639105 | 0.85 | CTSK (0.82) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6639111 | 0.85 | CTSK (0.82) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6639102 | 0.85 | CTSK (0.82) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL18540647 | 0.83 | CTSL (0.82) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4833031 | 0.81 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6700166 | 0.81 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6800595 | 0.80 | CTSK (0.66) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6800598 | 0.80 | CTSK (0.66) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1384713-A1 | 4-amino-azepan-3-one derivatives as protease inhibitors | SmithKline Beecham Corporation (US) | 2004-01-28 | — | — | EP | disclosed |