⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL29023790 | 0.87 | — | — | |
| SCHEMBL238145 | 0.74 | — | — | |
| SCHEMBL19443242 | 0.67 | — | — | |
| SCHEMBL28691124 | 0.67 | — | — | |
| SCHEMBL24447061 | 0.62 | — | — | |
| SCHEMBL78967 | 0.60 | TDP1 (0.36) | — | |
| SCHEMBL2020 | 0.59 | — | — | |
| SCHEMBL37550 | 0.59 | — | — | |
| SCHEMBL472031 | 0.59 | — | — | |
| SCHEMBL1332279 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210401948-A1 | POLYMER-FACTOR VIII MOIETY CONJUGATES | NEKTAR THERAPEUTICS (US) | 2021-12-30 | — | — | US | disclosed |
| CN-110483484-A | Sulfamoyl pyrrole amides derivative and its purposes for being used to treat hepatitis B as drug | JANSSEN SCIENCES IRELAND UC | 2019-11-22 | — | — | CN | disclosed |
| CN-105980378-B | Sulfamoyl pyrrole amide derivative and application thereof as medicine for treating hepatitis B | 爱尔兰詹森科学公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-110003076-A | Sulfamoyl pyrrole amides derivative and its purposes for being used to treat hepatitis B as drug | 爱尔兰詹森科学公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-105732414-B | The method of control of amide derivatives, the noxious organism control agent containing the amide derivatives and harmful organism | 三井化学AGRO株式会社 | 2019-05-03 | — | — | CN | disclosed |
| CN-105452220-B | Sulfamoyl pyrrole amide derivative and application thereof as medicine for treating hepatitis B | 爱尔兰詹森科学公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-105658624-B | Carboxamides derivatives and its purposes for being used to treat hepatitis B as drug | 爱尔兰詹森科学公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-108047115-A | Pyrrole amides derivative through acetaldehyde amide substitution and its as drug for treating the purposes of hepatitis B | 爱尔兰詹森科学公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-105431413-B | Glyoxylamide-substituted pyrrole amide derivatives and their use as medicaments for the treatment of hepatitis B | 爱尔兰詹森科学公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-104955824-B | It is used as the aminopyrimidine compounds of the inhibitor of the EGFR mutant containing T790M | 豪夫迈·罗氏有限公司 | 2017-09-22 | — | — | CN | disclosed |
| CN-102365279-A | Hydroxy-methyl isoxazole derivatives as gaba a modulators | HOFFMANN LA ROCHE | 2012-02-29 | — | — | CN | disclosed |
| CN-100519559-C | 6-[(substituted)phenyl]triazolopyrimidines as anticancer agents | WYETH CORP (US) | 2009-07-29 | — | — | CN | disclosed |
| CN-100488952-C | 5-phenyl pyridine, its preparation method and intermediate product and uses in controlling harmful fungus | BASF AG (DE) | 2009-05-20 | — | — | CN | disclosed |
| CN-1890245-A | Process for the preparation of tubulin inhibitors | WYETH CORP (US) | 2007-01-03 | — | — | CN | disclosed |
| CN-1867569-A | 6-[(substituted)phenyl]triazolopyrimidines as anticancer agents | WYETH CORP (US) | 2006-11-22 | — | — | CN | disclosed |
| CN-1802379-A | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2006-07-12 | — | — | CN | disclosed |
| CN-1525960-A | Lorenz Gisela | �����ɷ� | 2004-09-01 | — | — | CN | disclosed |
| EP-1392693-A1 | TRIAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002088126-A1 | TRIAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2002-11-07 | — | — | WO | disclosed |
| EP-0275203-A2 | Heat-sensitive recording material containing color forming components | FUJI PHOTO FILM CO., LTD. (JP) | 1988-07-20 | — | — | EP | disclosed |