Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6061712 | 0.88 | MAPT (0.46) | MAPTACHEBCHECA1CA2 | |
| SCHEMBL6628449 | 0.88 | MAPT (0.46) | MAPTACHEBCHECA1CA2 | |
| SCHEMBL6628343 | 0.83 | ACACB (0.36) | CYP3A4SCN9AACACB | |
| SCHEMBL6628340 | 0.83 | ACACB (0.36) | CYP3A4SCN9AACACB | |
| SCHEMBL6627857 | 0.83 | ACACB (0.36) | CYP3A4SCN9AACACB | |
| SCHEMBL6633248 | 0.82 | LMNA (0.35) | MAPT | |
| SCHEMBL6062057 | 0.81 | CTSS (0.41) | MAPTSCN9AACACB | |
| SCHEMBL6062065 | 0.81 | CTSS (0.41) | MAPTSCN9AACACB | |
| SCHEMBL6062062 | 0.81 | CTSS (0.41) | MAPTSCN9AACACB | |
| SCHEMBL6696297 | 0.81 | CTSS (0.41) | MAPTSCN9AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397340-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002098850-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | disclosed |