Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.80 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.80 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.75 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | CRHBP | P24387 | 1/20 | 0.68 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | ACHE | P22303 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28130871 | 0.89 | ESR1 (1.00) | ESR1ESR2CYP19A1ABCG2POLB | |
| SCHEMBL30269741 | 0.89 | ESR1 (1.00) | ESR1ESR2CYP19A1ABCG2POLB | |
| SCHEMBL31551707 | 0.89 | ESR1 (1.00) | ESR1ESR2CYP19A1ABCG2POLB | |
| SCHEMBL665265 | 0.87 | CYP19A1 (0.84) | ESR1ESR2CYP19A1ABCG2POLB | |
| SCHEMBL27715512 | 0.86 | PLK1 (0.68) | ESR1ESR2CYP19A1ABCG2POLB | |
| SCHEMBL22422611 | 0.84 | ESR1 (0.73) | ESR1ESR2CYP19A1ABCG2POLB | |
| Demethoxymatteucinol SCHEMBL29204370 | 0.83 | ABCG2 (0.64) | ESR1ESR2CYP19A1ABCG2POLB | |
| Demethoxymatteucinol SCHEMBL664144 | 0.83 | ABCG2 (0.64) | ESR1ESR2CYP19A1ABCG2POLB | |
| SCHEMBL9063227 | 0.83 | CYP19A1 (0.70) | ESR1ESR2CYP19A1ABCG2POLB | |
| SCHEMBL1068874 | 0.82 | PLK1 (0.67) | ESR1ESR2CYP19A1ABCG2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238274-A1 | INHIBITORS OF UBIQUITIN SPECIFIC PEPTIDASE 22 (USP22) AND USES THEREOF FOR TREATING DISEASE AND DISORDERS | NORTHWESTERN UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
| US-20240238274-A1 | INHIBITORS OF UBIQUITIN SPECIFIC PEPTIDASE 22 (USP22) AND USES THEREOF FOR TREATING DISEASE AND DISORDERS | NORTHWESTERN UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
| WO-2023004473-A1 | METHODS AND COMPOUNDS FOR SKIN CONDITIONS | UNIVERSITY OF THE SUNSHINE COAST (AU) | 2023-02-02 | — | — | WO | disclosed |
| US-20120046353-A1 | CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS | CHOONG ANG VACCINE LAB. (KR) | 2012-02-23 | — | — | US | disclosed |
| EP-0742012-A2 | Pharmaceutical composition containing substance inhibiting HSP47 production | Kureha Chemical Industry Co., Ltd. (JP) | 1996-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046353-A1 | CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS | PIGS, CLEC4M, ENGASE | ESR1 3607/4885ESR2 4084/4885CYP19A1 4094/4885 |
| US-20240238274-A1 | INHIBITORS OF UBIQUITIN SPECIFIC PEPTIDASE 22 (USP22) AND USES THEREOF FOR TREATING DISEASE AND DISORDERS | USP19, USP24, USP2 | ESR1 3016/4885ESR2 1234/4885CYP19A1 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.