Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.52 |
| ▸ | CTSL | P07711 | 6/20 | 0.40 |
| ▸ | CTSB | P07858 | 5/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14427114 | 1.00 | CTSS (0.52) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL14488993 | 0.89 | CTSS (0.51) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL6636267 | 0.89 | CTSS (0.51) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL14427100 | 0.85 | CTSS (0.51) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL7043174 | 0.83 | CTSS (0.51) | CTSS | |
| SCHEMBL14427108 | 0.83 | CTSS (0.51) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL14427112 | 0.82 | CTSS (0.51) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL5387787 | 0.82 | ELANE (0.40) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL14427088 | 0.81 | CTSS (0.53) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL14427076 | 0.81 | CTSS (0.53) | CTSSCTSLCTSBCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446392-A1 | OLIGOPEPTIDES AND COMPOSITIONS CONTAINING THEM AS CATHEPSIN S INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2004-08-18 | — | — | EP | claimed |
| WO-2003042197-A1 | OLIGOPEPTIDES AND COMPOSITIONS CONTAINING THEM AS CATHEPSIN S INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2003-05-22 | — | — | WO | claimed |
| EP-1446392-A1 | OLIGOPEPTIDES AND COMPOSITIONS CONTAINING THEM AS CATHEPSIN S INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003042197-A1 | OLIGOPEPTIDES AND COMPOSITIONS CONTAINING THEM AS CATHEPSIN S INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2003-05-22 | — | — | WO | disclosed |