SCHEMBL6630680

SCHEMBL6630680

CCCCC[C@H](CO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14834118 0.85 CA2 (0.36) CA2
SCHEMBL18022040 0.84 CA2 (0.35) CA2
SCHEMBL26726102 0.81
SCHEMBL8496165 0.81 CA2 (0.36) CA2
SCHEMBL16692369 0.81 CA2 (0.34) CA2
SCHEMBL19385898 0.81 LMNA (0.35) CA2
SCHEMBL22391538 0.79 LMNA (0.38) CA2
SCHEMBL22391537 0.79 LMNA (0.38) CA2
SCHEMBL14716894 0.79 CA2 (0.33) CA2
SCHEMBL11256681 0.79 CA2 (0.33) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1490341-A1 NOVEL ADAMANTANE DERIVATIVES AstraZeneca AB (SE) 2004-12-29 EP disclosed
WO-2003080579-A1 NOVEL ADAMANTANE DERIVATIVES ASTRAZENECA AB (SE) 2003-10-02 WO disclosed