Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6369881 | 0.82 | ALDH1A1 (0.50) | CYP2C19ABCB11ALDH1A1ADRA2ACYP2B6 | |
| SCHEMBL5242060 | 0.81 | ALDH1A1 (0.49) | CYP2C19ABCB11ALDH1A1ADRA2ACYP2B6 | |
| SCHEMBL28687701 | 0.80 | CYP2C19 (0.55) | CYP2C19ABCB11ALDH1A1ADRA2ACYP2B6 | |
| Water SCHEMBL11003040 | 0.80 | ALDH1A1 (0.47) | CYP2C19ABCB11ALDH1A1ADRA2ACYP2B6 | |
| SCHEMBL5862011 | 0.78 | KMT2A (0.61) | ALDH1A1MAPK1KDM4ETSHRPRMT5 | |
| SCHEMBL8801055 | 0.77 | CYP2C19 (0.47) | CYP2C19ABCB11ALDH1A1ADRA2ACYP2B6 | |
| Hydrochloric Acid SCHEMBL6635562 | 0.76 | MAPK1 (0.57) | CYP2C19ABCB11ALDH1A1ADRA2ACYP2B6 | |
| SCHEMBL8802005 | 0.76 | ALDH1A1 (0.53) | CYP2C19ABCB11ALDH1A1ADRA2ACYP2B6 | |
| Hydrochloric Acid SCHEMBL6659698 | 0.76 | NPSR1 (0.45) | CYP2C19ABCB11ALDH1A1ADRA2ACYP2B6 | |
| Hydrochloric Acid SCHEMBL6659697 | 0.76 | CYP2C19 (0.48) | CYP2C19ABCB11ALDH1A1ADRA2ACYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656381-B1 | CRYSTALLISATION OF SOLID FORMS OF CLOPIDOGREL ADDITION SALTS | KRKA TORVARNA ZDRAVIL D D NOVO MESTO (SI) | 2011-03-09 | — | — | EP | disclosed |
| CN-100522970-C | Stereoselective method for the production of clopidogrel | RATIOPHARM GMBH (DE) | 2009-08-05 | — | — | CN | disclosed |
| CN-1318428-C | Thiophenopyridine substituted acetyl hyarazine derivative | TIANJIN MEDICINE INST (CN) | 2007-05-30 | — | — | CN | disclosed |
| CN-1972950-A | Stereoselective process for preparing clopidogrel | RATIOPHARM GMBH (DE) | 2007-05-30 | — | — | CN | disclosed |
| CN-1683373-A | Thiophenopyridine substituted acetyl hyarazine derivative | TIANJIN MEDICINE INST (CN) | 2005-10-19 | — | — | CN | disclosed |
| EP-1438314-A1 | A PROCESS FOR PREPARING ENANTIOMERICALLY PURE ALPHA-PHENYL-APLPHA(6,7-DIHYDRO-4H-THIENO 3,2-C PYRIDIN-5-YL)-ACETIC ACID DERIVATIVES | Merck Generics (UK) Limited (GB) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003035652-A9 | A PROCESS FOR PREPARING ENANTIOMERICALLY PURE α-PHENYL-α-(6,7-DIHYDRO-4H-THIENO[3,2-C]PYRIDIN-5-YL)-ACETIC ACID DERIVATIVES | MERCK GENERICS UK LTD (GB) | 2004-04-08 | — | — | WO | disclosed |
| WO-2003035652-A1 | A PROCESS FOR PREPARING ENANTIOMERICALLY PURE α-PHENYL-α-(6,7-DIHYDRO-4H-THIENO[3,2-C]PYRIDIN-5-YL)-ACETIC ACID DERIVATIVES | MERCK GENERICS [UK] LIMITED (GB) | 2003-05-01 | — | — | WO | disclosed |