Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10623034 | 0.86 | DRD3 (0.59) | ALDH1A1KDM4ECYP2C19DRD3HTR2B | |
| SCHEMBL6369881 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4ECASP1CYP2C19DRD3 | |
| SCHEMBL5242060 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4ECASP1CYP2C19DRD3 | |
| Water SCHEMBL11003040 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4ECASP1CYP2C19DRD3 | |
| SCHEMBL8801055 | 0.79 | CYP2C19 (0.47) | ALDH1A1KDM4ECASP1CYP2C19DRD3 | |
| SCHEMBL3381087 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KDM4ECASP1CYP2C19DRD3 | |
| SCHEMBL28687701 | 0.76 | CYP2C19 (0.55) | ALDH1A1KDM4ECASP1CYP2C19DRD3 | |
| SCHEMBL6631313 | 0.76 | CYP2C19 (0.49) | ALDH1A1KDM4ECASP1CYP2C19DRD3 | |
| SCHEMBL3992345 | 0.75 | HSP90AA1 (0.52) | ALDH1A1LMNASMN1; SMN2AKR1C3PRMT5 | |
| SCHEMBL30546565 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KDM4ECASP1CYP2C19DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522956-B1 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI SA (FR) | 1997-02-05 | — | — | EP | disclosed |
| US-5191090-A | Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno[3,2-c]pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |
| US-5068360-A | Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno(3,2-C)pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0439404-A2 | Preparation of 2-(2'-thienyl) alkylamines and derivatives thereof and synthesis of 4,5,6,7- thieno [3,2-c] pyridine derivatives therefrom | SANOFI (FR) | 1991-07-31 | — | — | EP | disclosed |
| US-4997945-A | Ticlopidine intermediate | SYNTEX (U.S.A.) INC. (US) | 1991-03-05 | — | — | US | disclosed |
| US-4906756-A | 2-(2-nitrovinyl)thiophene reduction and synthesis of thieno[3,2-c]pyridine derivatives | SYNTEX (U.S.A.) INC. (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0342118-A1 | 2-(2-nitrovinyl)thiophene reduction and synthesis of thieno (3,2-c)pyridine derivatives | ELF SANOFI (FR) | 1989-11-15 | — | — | EP | disclosed |