SCHEMBL6631398

SCHEMBL6631398

O=S(=O)(O)c1ccc2c(O)[c]ccc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
CASP6 P55212 4/20 0.47
HSD17B10 Q99714 4/20 0.47
CYP2C9 P11712 3/20 0.47
CYP2C19 P33261 2/20 0.47
NSD2 O96028 3/20 0.45
NT5E P21589 3/20 0.45
DUSP3 P51452 2/20 0.45
PTPN5 P54829 2/20 0.45
PTPN11 Q06124 2/20 0.45
PRMT1 Q99873 1/20 0.42
CYP1A2 P05177 3/20 0.42
HIF1A Q16665 3/20 0.40
TSHR P16473 1/20 0.40
PTPRA P18433 1/20 0.40
PTPRB P23467 1/20 0.40
RAPGEF4 Q8WZA2 1/20 0.40
TDP1 Q9NUW8 2/20 0.40
HPGD P15428 2/20 0.40
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6633540 0.86 ALDH1A1 (0.47) ALDH1A1CASP6HSD17B10CYP2C9CYP2C19
SCHEMBL4904953 0.83 ALDH1A1 (0.47) ALDH1A1CASP6HSD17B10CYP2C9CYP2C19
SCHEMBL6632503 0.82 NT5E (0.33) ALDH1A1CASP6HSD17B10CYP2C9CYP2C19
SCHEMBL11315411 0.81 CASP6 (0.54) ALDH1A1CASP6HSD17B10CYP2C9CYP2C19
SCHEMBL6630593 0.76 CASP6 (0.49) ALDH1A1CASP6HSD17B10CYP2C9CYP2C19
SCHEMBL6632477 0.75 ALDH1A1 (0.42) ALDH1A1CASP6HSD17B10CYP2C9CYP2C19
SCHEMBL2210354 0.75 CASP6 (0.47) ALDH1A1CASP6HSD17B10CYP2C9CYP2C19
SCHEMBL5034793 0.74 CYP1A2 (0.38) ALDH1A1HSD17B10CYP1A2HIF1ATSHR
SCHEMBL6631900 0.72 ALDH1A1 (0.47) ALDH1A1CASP6HSD17B10CYP2C9CYP2C19
SCHEMBL6631111 0.72 ALDH1A1 (0.40) ALDH1A1CASP6HSD17B10CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040231558-A1 Has a clear hue, high light fastness and high moisture resistance MITSUI CHEMICALS, INC. (JP) 2004-11-25 US disclosed
EP-1441013-A1 WATERCOLOR INK Mitsui Chemicals, Inc. (JP) 2004-07-28 EP disclosed