Pyridazine

Pyridazine

SCHEMBL663154

c1cc2ccc1-2.c1ccnnc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
NOTUM Q6P988 1/20 0.40
ALDH1A1 P00352 4/20 0.38
CYP1A2 P05177 3/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
CCR1 P32246 1/20 0.35
CCR5 P51681 1/20 0.35
CCR8 P51685 1/20 0.35
METAP1 P53582 1/20 0.35
BLM P54132 1/20 0.35
HIF1A Q16665 1/20 0.35
DOHH Q9BU89 1/20 0.35
P4HTM Q9NXG6 1/20 0.35
CYP3A4 P08684 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
KIF11 P52732 2/20 0.33
MAPK1 P28482 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27478909 0.86 ALDH1A1 (0.60) NOTUMALDH1A1CYP1A2CYP3A4TDP1
Pyridazine SCHEMBL28875671 0.79 TSHR (0.36) TDP1
Pyridazine SCHEMBL29471424 0.78
Pyridazine SCHEMBL5104 0.78
Pyridazine SCHEMBL11423 0.78 TSHR (0.42) TDP1
Pyridazine SCHEMBL462827 0.76 MEN1 (0.43) NOTUMALDH1A1CYP1A2CYP3A4KIF11
Pyridazine SCHEMBL21405425 0.74
Pyridazine SCHEMBL21626119 0.74 TSHR (0.39) TDP1
Pyridazine SCHEMBL5361937 0.74
Pyridazine SCHEMBL21222853 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024223966-A1 SOLID COLOURING AGENT EMULSION FOR MANUFACTURING HAIR DYE ROCA PARES ALBERT (ES) 2024-10-31 WO claimed
EP-4454633-A1 SOLID COLOURING AGENT EMULSION FOR MANUFACTURING HAIR DYE Roca Pares, Albert (ES) 2024-10-30 EP claimed
EP-3229919-B1 COMPOSITION AND PROCEDURE FOR TREATING KERATIN-CONTAINING FIBERS WITH FLASH EVAPORATION HENKEL AG & CO KGAA (DE) 2024-03-13 EP claimed
WO-2022139044-A1 METHOD FOR PREPARING GRAPHENE-CARBON NANOTUBE COMPOSITE (주)카본티앤씨 2022-06-30 WO claimed
US-10934171-B2 Functionalized graphene comprising two or more types of amines, and preparation method therefor DONGJIN SEMICHEM CO., LTD. (KR) 2021-03-02 US claimed
US-20180079647-A1 FUNCTIONALIZED GRAPHENE COMPRISING TWO OR MORE TYPES OF AMINES, AND PREPARATION METHOD THEREFOR DONGJIN SEMICHEM CO., LTD. 2018-03-22 US claimed
EP-2252625-B1 CIS REACTIVE OXYGEN QUENCHERS INTEGRATED INTO LINKERS PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2017-12-20 EP claimed
EP-2103299-B1 Oxidizing hair colourant compositions PROCTER & GAMBLE (US) 2013-02-27 EP claimed
EP-2476657-A1 TEMPERATURE-ADJUSTED AND MODIFIED RECYCLED ASCON COMPOSITION FOR REUSING 100% OF WASTE ASCON FOR ROAD PAVEMENT, AND METHOD FOR MANUFACTURING SAME Huh, Jung Do (KR) 2012-07-18 EP claimed
CN-102448907-A Temperature-adjusted and modified recycled ascon composition for reusing 100% of waste ascon for road pavement, and method for manufacturing same DO HUH JUNG 2012-05-09 CN claimed
WO-2011027926-A1 TEMPERATURE-ADJUSTED AND MODIFIED RECYCLED ASCON COMPOSITION FOR REUSING 100% OF WASTE ASCON FOR ROAD PAVEMENT, AND METHOD FOR MANUFACTURING SAME HUH JUNG DO (KR) 2011-03-10 WO claimed
US-7597720-B2 Oxidizing hair colourant compositions THE PROCTER & GAMBLE COMPANY (US) 2009-10-06 US claimed
EP-2103299-A2 Oxidizing hair colourant compositions The Procter and Gamble Company (US) 2009-09-23 EP claimed
US-20090119852-A1 Oxidizing Hair Colourant Compositions WELLA OPERATIONS US, LLC 2009-05-14 US claimed
WO-2009060334-A2 OXIDIZING HAIR COLOURANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2009-05-14 WO claimed
US-RE35292-E CONCENTRATING BY PASSING THROUGH AROMATIC POLYAMIDE SEMIPERMEABLE MEMBRANE; DIALYSIS, ULTRAFILTRATION HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-09 US claimed
US-5174899-A Ultrafiltration or dialysis with semipermeable aromatic polyamide membranes HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-29 US claimed
JP-55092111-A None JP disclosed
JP-S5592111-A PREPARING CATIONIC HIGH MOLECULAR COAGULANT KONAN KAGAKU KOGYO KK 1980-07-12 JP disclosed
US-4153460-A Light-sensitive silver halide color photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD (JP) 1979-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090119852-A1 Oxidizing Hair Colourant Compositions TET1, TET2, TET3 LMNA 4051/4885MAPT 1470/4885NOTUM 1007/4885
US-10934171-B2 Functionalized graphene comprising two or more types of amines, and preparation method therefor WASF2, WEE2, ITGAV LMNA 2553/4885MAPT 1826/4885NOTUM 580/4885
US-20180079647-A1 FUNCTIONALIZED GRAPHENE COMPRISING TWO OR MORE TYPES OF AMINES, AND PREPARATION METHOD THEREFOR WASF2, WEE2, ITGAV LMNA 2553/4885MAPT 1826/4885NOTUM 580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.