Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634464 | 0.92 | NPY2R (0.36) | NPY2RALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6635395 | 0.92 | NPY2R (0.38) | NPY2RALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6632912 | 0.85 | NPY2R (0.36) | NPY2RALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6637256 | 0.80 | NPY2R (0.38) | NPY2RALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6659012 | 0.78 | NPY2R (0.35) | NPY2RALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6638472 | 0.78 | NPY2R (0.40) | NPY2RALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6663224 | 0.77 | CYP1A2 (0.44) | NPY2RALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6633212 | 0.76 | NPY2R (0.37) | NPY2RALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3852314 | 0.76 | ITGB1 (0.39) | NPY2RALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3850655 | 0.75 | P2RX7 (0.40) | NPY2RALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |