Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 11/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634647 | 0.84 | ESR2 (0.42) | CYP1A2ESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL4474923 | 0.75 | CYP1A2 (0.54) | CYP1A2CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL670670 | 0.70 | CYP1A2 (0.52) | CYP1A2ESR1ESR2MCL1CYP3A4 | |
| SCHEMBL4963546 | 0.70 | NQO2 (0.60) | CYP1A2ESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL31037129 | 0.70 | NQO2 (0.60) | CYP1A2ESR1ESR2CYP3A4ALOX15 | |
| SCHEMBL29738648 | 0.68 | CTDSP1 (0.63) | CYP1A2ESR1ESR2MCL1CYP3A4 | |
| SCHEMBL29616 | 0.68 | CTDSP1 (0.63) | CYP1A2ESR1ESR2MCL1CYP3A4 | |
| SCHEMBL29352754 | 0.68 | CTDSP1 (0.63) | CYP1A2ESR1ESR2MCL1CYP3A4 | |
| Water SCHEMBL15639792 | 0.68 | ESR1 (0.43) | CYP1A2ESR1ESR2MCL1CYP3A4 | |
| SCHEMBL8675127 | 0.67 | HSD17B1 (0.61) | CYP1A2ESR1ESR2MCL1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096657-B1 | 2-PHENYL-2-NAPHTHYL AND 2-HETEROCYCLIC PYRIMIDINES AS ANTIDOTES FOR PROTECTING CULTURED PLANTS BEFORE PHYTOTOXIC DAMAGES CAUSED BY HERBICIDES | CIBA-GEIGY AG (CH) | 1989-04-05 | — | — | EP | claimed |
| EP-0096657-A2 | 2-Phenyl-2-naphthyl and 2-heterocyclic pyrimidines as antidotes for protecting cultured plants before phytotoxic damages caused by herbicides | CIBA-GEIGY AG (CH) | 1983-12-21 | — | — | EP | claimed |
| CN-1276035-C | Water-color ink | MITSUI CHEMICALS INC (JP) | 2006-09-20 | — | — | CN | disclosed |
| CN-1558934-A | Water-color ink | 三井化学株式会社 | 2004-12-29 | — | — | CN | disclosed |
| US-20040231558-A1 | Has a clear hue, high light fastness and high moisture resistance | MITSUI CHEMICALS, INC. (JP) | 2004-11-25 | — | — | US | disclosed |
| EP-1441013-A1 | WATERCOLOR INK | Mitsui Chemicals, Inc. (JP) | 2004-07-28 | — | — | EP | disclosed |
| EP-0096657-B1 | 2-PHENYL-2-NAPHTHYL AND 2-HETEROCYCLIC PYRIMIDINES AS ANTIDOTES FOR PROTECTING CULTURED PLANTS BEFORE PHYTOTOXIC DAMAGES CAUSED BY HERBICIDES | CIBA-GEIGY AG (CH) | 1989-04-05 | — | — | EP | disclosed |
| US-4698091-A | 2-phenylpyrimidines, 2-naphthylpyrimidines and 2-heterocyclylpyrimidines as safeners for protecting cultivated plant against phytotoxic damage caused by herbicides | CIBA-GEIGY CORPORATION (US) | 1987-10-06 | — | — | US | disclosed |
| EP-0096657-A2 | 2-Phenyl-2-naphthyl and 2-heterocyclic pyrimidines as antidotes for protecting cultured plants before phytotoxic damages caused by herbicides | CIBA-GEIGY AG (CH) | 1983-12-21 | — | — | EP | disclosed |